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Psychopathology in Down Syndrome
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- Childhood Onset of 'Adult' Psychopathology: Clinical and Research Advances - Google Books;
- Childhood Onset of 'Adult' Psychopathology: Clinical and Research Advances - Google Books.
- Stress load during childhood affects psychopathology in psychiatric patients.
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Download references. We acknowledge the assistance of K. Matz and S.
Unfried in data acquisition. Correspondence to Brigitte Rockstroh. BR designed the study protocol, supervised the study and wrote the manuscript together with KW. Reprints and Permissions. Search all BMC articles Search. Abstract Background Childhood stress and trauma have been related to adult psychopathology in different psychiatric disorders. Methods 96 patients with diagnoses of Major Depressive Disorder MDD , schizophrenia, drug addiction, or personality disorders PD and 31 subjects without psychiatric diagnosis were screened for adverse experiences in childhood before the age of six years , before onset of puberty, and in adulthood using the Early Trauma Inventory and the Posttraumatic Stress Diagnostic Scale.
Results High stress load in childhood and before puberty, but not in adulthood, was related to negative affect in all participants. Conclusion Results support the hypothesis of stress-sensitive periods during development, which may interact with genetic and other vulnerability factors in their influence on the progress of psychiatric disorders. Open Peer Review reports. Background A burgeoning number of studies point to the influence of adverse or traumatic experiences during childhood on adult psychopathology [ 1 — 7 ]. Methods Participants Altogether inpatients of a local Center for Psychiatry Zentrum fuer Psychiatrie Reichenau and 36 individuals without psychiatric diagnoses were engaged in the study.
Results A significantly higher number of stressful events and higher stress load before puberty was found in psychiatric patients compared to healthy subjects see Table 2 for means, standard deviations, group differences. Figure 1.
Full size image. DSM and the death of phenomenology in America: an example of unintended consequences. The near Babylonian speech confusion in early detection of psychosis. Psychosis-risk criteria in the general population: frequent misinterpretations and current evidence.
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Minnesota Center for Twin and Family Research
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